Middle-age Asian male with cerebral venous thrombosis after COVID-19 AstraZeneca vaccination.

Vaccine-associated cerebral venous thrombosis has become an issue following the extensive vaccination program of the Coronavirus Disease of 2019 (COVID-19) Vaccine AstraZeneca (ChAdOx1 vaccine). The importance of early diagnosis should be emphasized due to the high mortality rate without appropriate treatment. Young female populations in western countries have been reported to be at a greater risk of this vaccine related thrombotic event, but cases in East Asia are lacking. Herein, we present the first case of cerebral venous sinus thrombosis 10 days after ChAdOx1 vaccination in a middle-age Asian male in Taiwan.

Analysis of prognostic factors of patients with corona virus disease 2019 in Hefei, China

Objective To explore the relationship of prognosis of Corona Virus Disease 2019 (COVID-19) with age and inflammation. Methods The clinical data of 72 patients with COVID-19 in Hefei were collected. The levels of serum C-reactive protein (CRP), interleukin-6 (IL-6), procalcitonin (PCT), erythrocyte sedimentation rate (ESR) were measured. The data was stratified and analyzed according to age, gender and severity of the disease. Results Among the elderly patients with COVID- 19, the proportion of the patients with basic diseases and severe disease was significantly higher, and the proportion of healers was significantly lower than that of other age groups (P<0.05). The levels of IL-6 and CRP in the elderly patients with COVID-19 were significantly higher than those in other age groups (P<0.05) . The levels of IL-6 and CRP in the severe patients were significantly higher than those in the mild patients (P< 0.05) . Conclusions Age and inflammation may increase the patients' susceptibility to the new coronavirus, and also adversely affect the patients' prognosis and outcome.

Online Health Information Seeking Using "#COVID-19 Patient Seeking Help" on Weibo in Wuhan, China: Descriptive Study.

BACKGROUND: First detected in Wuhan, China in December 2019, the COVID-19 pandemic stretched the medical system in Wuhan and posed a challenge to the state's risk communication efforts. Timely access to quality health care information during outbreaks of infectious diseases can be effective to curtail the spread of disease and feelings of anxiety. Although existing studies have extended our knowledge about online health information-seeking behavior, processes, and motivations, rarely have the findings been applied to an outbreak. Moreover, there is relatively little recent research on how people in China are using the internet for seeking health information during a pandemic. OBJECTIVE: The aim of this study is to explore how people in China are using the internet for seeking health information during a pandemic. Drawing on previous research of online health information seeking, this study asks the following research questions: how was the "#COVID-19 Patient Seeking Help" hashtag being used by patients in Wuhan seeking health information on Weibo at the peak of the outbreak? and what kinds of health information were patients in Wuhan seeking on Weibo at the peak of the outbreak? METHODS: Using entity identification and textual analysis on 10,908 posts on Weibo, we identified 1496 patients with COVID-19 using "#COVID-19 Patient Seeking Help" and explored their online health information-seeking behavior. RESULTS: The curve of the hashtag posting provided a dynamic picture of public attention to the COVID-19 pandemic. Many patients faced difficulties accessing offline health care services. In general, our findings confirmed that the internet is used by the Chinese public as an important source of health information. The lockdown policy was found to cut off the patients' social support network, preventing them from seeking help from family members. The ability to seek information and help online, especially for those with young children or older adult members during the pandemic. A high proportion of female users were seeking health information and help for their parents or for older adults at home. The most searched information included accessing medical treatment, managing self-quarantine, and offline to online support. CONCLUSIONS: Overall, the findings contribute to our understanding of health information-seeking behaviors during an outbreak and highlight the importance of paying attention to the information needs of vulnerable groups and the role social media may play.